Endosomal trafficking of yeast membrane proteins

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Biochem Soc Trans. 2018 October

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Laidlaw K &  MacDonald C.

COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin

sorting signal

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eLife. 2017 October

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Xu P, Hankins HM, MacDonald C, Erlinger SJ, Frazier MN, Diab NS, Piper RC, Jackson LP, 

MacGurn JA, Graham TR

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Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases

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Journal of Cell Biology. 2017 August

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MacDonald C & Piper RC.

Enzyme reversal to explore the function of yeast E3 ubiquitin-ligases.

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Traffic. 2017 July

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MacDonald C, Winistorfer S, Pope RM, Wright ME, Piper RC.

2016

Cell surface recycling in yeast: mechanisms and machineries.

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Biochem Soc Trans. 2016 April

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MacDonald C*,  Piper RC.   * = corresponding author

2015

Tetraspan cargo adaptors usher GPI-anchored proteins into multivesicular bodies.

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Cell Cycle. 2015 October

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MacDonald C, Stamnes MA, Katzmann DJ, Piper RC

A family of tetraspans organizes cargo for sorting into multivesicular bodies.

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Dev. Cell. 2015 May

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MacDonald C, Payne JA, Aboian M, Smith W, Katzmann DJ, Piper RC.

Puromycin- and methotrexate-resistance cassettes and optimized Cre-recombinase expression plasmids for use in yeast.

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Yeast. 2015 May

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MacDonald C*, Piper RC.   * = corresponding author

2013

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.

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eLife. 2013 August

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Kamadurai HB, Qiu Y, Deng A, Harrison JS, Macdonald C, Actis M, Rodrigues P, Miller DJ, Souphron J, Lewis SM, Kurinov I, Fujii N, Hammel M, Piper R, Kuhlman B, Schulman BA.

2012

Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation.

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EMBO Rep. 2012 April

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MacDonald C, Buchkovich NJ, Stringer DK, Emr SD, Piper RC.

Sna3 is an Rsp5 adaptor protein that relies on ubiquitination for its MVB sorting.

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Traffic. 2012 April

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MacDonald C, Stringer DK, Piper RC.

2010

Autoinhibition of SNARE complex assembly by a conformational switch represents a conserved feature of syntaxins.

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Biochem. Soc. Trans. 2010 February.

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MacDonald C, Munson M, Bryant NJ.

2009

The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p.

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Proc. Natl. Acad. Sci. U S A. 2009 August

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Furgason ML, MacDonald C, Shanks SG, Ryder SP, Bryant NJ, Munson M.

Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism.

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J. Cell Sci. 2009 April

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Struthers MS*, Shanks SG*, MacDonald C*, Carpp LN, Drozdowska AM, Kioumourtzoglou D, Furgason ML, Munson M, Bryant NJ.   * = shared authorship