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Biology Department
MacDonald Lab
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Publications
2022
The effect of lithium on the budding yeast
Saccharomyces cerevisiae
upon stress adaptation
Microorganisms
Reith P, Braam S, Welkenhuysen N, Lecinski S, Shepherd J, MacDonald C, Leake MC, Hohmann S,
Shashkova S, Cvijovic M.
Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation
Molecular Biology of the Cell
Laidlaw KM, Paine KM, Bisinski DD, Calder G, Hogg K, Ahmed S, James S, O’Toole PJ, MacDonald C.
2021
The Rpd3-complex regulates expression of multiple cell surface recycling factors in yeast
International Journal of Molecular Science
Amoiradaki K, Bunting KR, Paine KM, Ayre JE, Hogg K, Laidlaw KM, MacDonald C.
Investigating molecular crowding during cell division and hyperosmotic stress in budding yeast with FRET
Current Topics in Membranes
Lecinski S*, Shepherd JW*, Frame L, Hayton I, MacDonald C, Leake MC.
Fur4 mediated uracil-scavenging to screen for surface protein regulators
Traffic
Paine K, Ecclestone G, MacDonald C.
A glucose-starvation response governs endocytic trafficking and eisosomal retention surface cargoes in budding yeast
Journal of Cell Science
Laidlaw K, Bisinski D, Shashkova S, Paine K, Veillon M, Leake M, MacDonald C.
2020
Molecular crowding in single eukaryotic cells: using cell environment biosensing and single-molecule optical microscopy to probe dependence on extracellular ionic strength, local glucose conditions, and sensor copy number
Methods
Shepherd JW, Lecinski S, Wragg J, Shashkova S, MacDonald C, Leake MC.
A Cycle of Ubiquitination Regulates Adaptor Function of the Nedd4-Family Ubiquitin Ligase Rsp5
Current Biology
MacDonald C, Shields SB, Williams CA, Winistorfer SC, Piper RC.
2018
Endosomal trafficking of yeast membrane proteins
Biochemical Society Transactions
Laidlaw K & MacDonald C.
2017
COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal
eLife
Xu P, Hankins H, MacDonald C, Erlinger S, Frazier M, Diab N, Piper RC, Jackson L, MacGurn J, Graham T.
Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases
Journal of Cell Biology
MacDonald C & Piper RC.
Enzyme reversal to explore the function of yeast E3 ubiquitin-ligases
Traffic
MacDonald C, Winistorfer SC, Pope M, Wight ME, Piper RC.
2016
Cell surface recycling in yeast: mechanisms and machineries
Biochemical Society Transactions
MacDonald C & Piper RC.
2015
Tetraspan cargo adaptors usher GPI-anchored proteins into multivesicular bodies
Cell Cycle
MacDonald C, Stamnes MA, Katzmann, DJ & Piper RC.
Puromycin and methotrexate resistance cassettes and optimized Cre-recombinase expression plasmids for use in yeast
Yeast
MacDonald C & Piper RC.
A Family of Tetraspans Organizes Cargo for Sorting into Multivesicular Bodies
Developmental Cell
MacDonald C, Payne, JA, Aboian, M, Smith W, Katzmann, DJ & Piper RC.
2013
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
eLife
Kamadurai HB, Qiu Y, Deng A, Harrison JS, MacDonald C, Actis M, Rodrigues P, Miller DJ, Souphron J, Lewis SM, Kurinov I, Fujii N, Hammel M, Piper R, Kuhlman B, Schulman BA.
2012
Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation
EMBO Reports
MacDonald C, Buchkovich NJ, Stringer DK, Emr SD, Piper RC.
Sna3 Is an Rsp5 Adaptor Protein that Relies on Ubiquitination for Its MVB Sorting
Traffic
MacDonald C, Stringer DK, Piper RC
.
2010
Autoinhibition of SNARE complex assembly by a conformational switch represents a conserved feature of syntaxins
Biochemical Society Transactions
MacDonald C, Munson M, Bryant NJ.
2009
The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p
Proceedings of the National Academy of Sciences
Furgason ML, MacDonald C, Shanks SG, Ryder SP, Bryant NJ, Munson M.
Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism
Journal of Cell Science
Struthers MS, Shanks SG, MacDonald C, Carpp LN, Drozdowska AM, Kioumourtzoglou D, Furgason ML, Munson M, Bryant NJ.