Publications

2018

Endosomal trafficking of yeast membrane proteins
Biochem Soc Trans. 2018 October
Laidlaw K &  MacDonald C.

2017

COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin
sorting signal
eLife. 2017 October
Xu P, Hankins HM, MacDonald C, Erlinger SJ, Frazier MN, Diab NS, Piper RC, Jackson LP, 
MacGurn JA, Graham TR
Genetic dissection of early endosomal recycling highlights a TORC1-independent role for Rag GTPases
Journal of Cell Biology. 2017 August
MacDonald C & Piper RC.
Enzyme reversal to explore the function of yeast E3 ubiquitin-ligases.
Traffic. 2017 July
MacDonald C, Winistorfer S, Pope RM, Wright ME, Piper RC.

2016

Cell surface recycling in yeast: mechanisms and machineries.
Biochem Soc Trans. 2016 April
MacDonald C*,  Piper RC.   * = corresponding author

2015

Tetraspan cargo adaptors usher GPI-anchored proteins into multivesicular bodies.
Cell Cycle. 2015 October
MacDonald C, Stamnes MA, Katzmann DJ, Piper RC
A family of tetraspans organizes cargo for sorting into multivesicular bodies.
Dev. Cell. 2015 May
MacDonald C, Payne JA, Aboian M, Smith W, Katzmann DJ, Piper RC.
Puromycin- and methotrexate-resistance cassettes and optimized Cre-recombinase expression plasmids for use in yeast.
Yeast. 2015 May
MacDonald C*, Piper RC.   * = corresponding author

2013

Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
eLife. 2013 August
Kamadurai HB, Qiu Y, Deng A, Harrison JS, Macdonald C, Actis M, Rodrigues P, Miller DJ, Souphron J, Lewis SM, Kurinov I, Fujii N, Hammel M, Piper R, Kuhlman B, Schulman BA.

2012

Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation.
EMBO Rep. 2012 April
MacDonald C, Buchkovich NJ, Stringer DK, Emr SD, Piper RC.
Sna3 is an Rsp5 adaptor protein that relies on ubiquitination for its MVB sorting.
Traffic. 2012 April
MacDonald C, Stringer DK, Piper RC.

2010

Autoinhibition of SNARE complex assembly by a conformational switch represents a conserved feature of syntaxins.
Biochem. Soc. Trans. 2010 February.
MacDonald C, Munson M, Bryant NJ.

2009

The N-terminal peptide of the syntaxin Tlg2p modulates binding of its closed conformation to Vps45p.
Proc. Natl. Acad. Sci. U S A. 2009 August
Furgason ML, MacDonald C, Shanks SG, Ryder SP, Bryant NJ, Munson M.
Functional homology of mammalian syntaxin 16 and yeast Tlg2p reveals a conserved regulatory mechanism.
J. Cell Sci. 2009 April
Struthers MS*, Shanks SG*, MacDonald C*, Carpp LN, Drozdowska AM, Kioumourtzoglou D, Furgason ML, Munson M, Bryant NJ.   * = shared authorship

The Science & 

Mathematics University

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